Tim, to answer your earlier question there has been a lot installed since I first reinstalled Win10. The HC Sim and CI-1 were the first things I installed and it worked fine. Sometime after that the CI-1 stopped connecting to the HC Sim. I'm not sure what program would be blocking it, but it doesn't work even in Safe Mode. It does show up in the list of USB devices and the drivers install correctly.
The only thing I can think of would be that my laptop may have had some deeper settings configured in order to run a program for work that has to communicate with the central server. That program is kind of a pain to work with and I'm leaning towards it as being the problem. It has to stay though.
CI-1 works fine on my desktop also running Win10, with most of the same programs on it (besides the work program).
-Kevin